Resident Evil 4
The current supreme leader of the ancient European cult of Los Illuminados.
With the help of Ramon Salazar, Saddler was able to revive the cult's former method of proselytizing with the Plaga parasite. The Plaga has two variants, the subordinate "dependent" type which can manipulate its host, and the dominant "control" type which can command dependent Plagas. The parasites allowed Saddler to take absolute control over the entire region. His ambition would not end there however, as he desired control of the world itself. The first step in his plan was the kidnapping of Ashley, the U.S. President's daughter.