This was Umbrellas experiment on how the T-Virus would effect sea creatures. They infected great whites with the virus in the hope they would improve their already vast strength and speed.
The project was abandoned after the virus had little effect on the sharks and showed no real improvement, the implementation of shark as B.O.W's seems to have a somewhat limited scope as well.
It is not known if any have survived the raccoon city incident. But it is known that the Caucasus Laboratory in Russia had resumed development on them for an unknown reason. It's safe to say they went down along with Sergei Vladimir and everything else at the facility.
Date: Feb 10 2015